BRETT Kavanaugh’s path to the US Supreme Court is all but assured after two senators said they will elect the conservative to the country’s highest court.

The announcements by Republican Susan Collins of Maine and Democrat Joe Manchin of West Virginia ended most of the suspense over the political battle – though Democrats insisted on arguing through the night.

Some of them continued raising concerns that Kavanaugh would push the court further to the right, including possible sympathetic rulings for President Donald Trump, the man who nominated him.

But the case against Kavanaugh had long since been taken over by allegations that he sexually abused women decades ago.

In the pivotal moment on Friday, Collins, perhaps the chamber’s most moderate Republican, proclaimed her support for Kavanaugh at the end of a Senate floor speech that lasted nearly 45 minutes.

She told fellow senators that Christine Blasey Ford’s dramatic testimony last week describing Kavanaugh’s alleged 1982 assault was “sincere, painful and compelling”.

But she said the FBI had found no corroborating evidence from witnesses whose names Ford had provided.

“We will be ill-served in the long run if we abandon the presumption of innocence and fairness, tempting though it may be,” she said. “We must always remember that it is when passions are most inflamed that fairness is most in jeopardy.”

The story is expected to conclude on Saturday afternoon with a final roll call almost solidly along party lines. That would mark an anti-climactic finale to a clash fought against the backdrop of the #MeToo movement and Trump’s unyielding support of the nominee, and opposing forces that left Kavanaugh’s fate in doubt for weeks.

Manchin, the only remaining undeclared politician, used an emailed statement to announce his support for Kavanaugh moments after Collins finished talking, making him the only Democrat supporting the nominee.

“My heart goes out to anyone who has experienced any type of sexual assault in their life,” Manchin said.

But he added that based on the FBI report: “I have found Judge Kavanaugh to be a qualified jurist who will follow the Constitution and determine cases based on the legal findings before him.”

Protesters chanted “shame” at Manchin later when he talked to reporters outside his office. Republicans control the Senate by a meagre 51-49 margin. Support from Collins and Manchin would give Kavanaugh at least 51 votes.

Republican Lisa Murkowski of Alaska, a fellow moderate and a friend of Collins, is the only Republican who has indicated she will vote no. She told reporters that Kavanaugh is “a good man” but maybe “not the right man for the court at this time”.

When Trump nominated Kavanaugh in July, Democrats leapt to oppose him, saying he seemed ready to rule for Trump if federal authorities probing his 2016 campaign’s alleged connections to Russia try to pursue him in court.

Yet Kavanaugh’s pathway to confirmation seemed unfettered until Ford accused him of drunkenly sexually assaulting her in a locked bedroom at a 1982 high school gathering.